Start this sheet when: Sudden airway (swelling, stridor, hoarse voice), breathing (wheeze, falling SpO2) or circulation (low BP, collapse) problem after a likely trigger, usually with skin or lip changes. A reaction inside the ED: enter the reaction time as the door time.
Time since door
--
1.IM adrenaline 0.5 mg (1 mg/mL) in the outer thigh
≤ 5 min from door · RC UK: the moment it is recognised
2.Second IM adrenaline dose(No improvement)
≤ 5 min from first adrenaline · RC UK: repeat after 5 min if no better
3.IV access and fluid bolus (500-1000 mL) running(Low BP or shock)
≤ 15 min from door · Local target: with the second dose
4.Low-dose IV adrenaline infusion started(Refractory)
≤ 15 min from second adrenaline · RC UK: refractory after two IM doses
5.Mast cell tryptase, first sample
≤ 1 h from door · RC UK: once treatment is under way
6.Mast cell tryptase, second sample
≤ 2 h from onset of reaction · RC UK: 1-2 h after onset, never after 4 h
7.Symptoms resolved
Record · Observation clock starts here
8.Disposition decided
Record · Admit / transfer / OT; for the length-of-stay audit
9.Patient left the ED
≤ 2 h from disposition decision · ED KPI: decision to departure 2 h or less
Targets marked “local” are suggestions: agree your own with the quality committee before auditing against them.